Screenshots can be a tricky thing; in my day job I take a lot for sharing with coworkers. The default Mac OS X behavior of dropping screenshots on the desktop is poor and leads to a lot of unnecessary cruft. I’m not super crazy about Dropbox’s implementation either, as their default file references include a Dropbox web UI around the image itself (I prefer the image raw.)
Naturally, this workflow for keyboard launcher Alfred fit my particular screenshot needs very well. I currently have two keyboard shortcuts set up; one allows me to select part of the screen, which then copies to a Dropbox folder and pastes the link to the raw image in my clipboard, the other just copies the image direct to clipboard for screenshots I know I won’t have to reference later.